Tuam Tshoj Supply Sarms Raw Sr9009 Stenabolic API

REV-ERBα thiab REV-ERBβ nuclear receptors yog transcriptional repressors uas tswj circadian atherosclerosis thiab metabolic txoj kev nyob rau hauv ib tug heme-dependent yam.SR9009 yog REV-ERB agonist uas ua rau muaj kev tsim txom ntawm cov noob tswj los ntawm REV-ERBα thiab REV-ERBβ nrog IC50 qhov tseem ceeb ntawm 670 thiab 800 nM, feem.1Los ntawm kev ua kom REV-ERB, SR9009 tau pom tias yuav txo qis circadian locomotor kev ua haujlwm thaum lub sijhawm tsaus ntuj thiab hloov pauv cov qauv qhia ntawm lub moos tseem ceeb hauv lub hypothalami ntawm nas.1Cov qauv circadian ntawm kev nthuav qhia ntawm ib qho array ntawm metabolic genes nyob rau hauv daim siab, skeletal nqaij thiab adipose ntaub so ntswg kuj pom tau hais tias yuav hloov nyob rau hauv cov nas raug rau SR9009, uas ua rau kom muaj zog kev siv nyiaj.1 Diet-induced obese nas kho nrog 100 mg / kg. SR9009 (ip ob zaug hauv ib hnub rau 30 hnub) tau tshaj tawm kom pom cov rog tsawg thiab ua kom zoo dua dyslipidemia thiab hyperglycemia.1

CEEB TOOM Cov khoom no tsis yog siv rau tib neeg lossis kws kho tsiaj.