Adipotide 2 mg txhaj

Adipotide (aka FTPP lossis proapototic peptide) tua cov rog rog, yooj yim thiab yooj yim, los ntawm kev tsom mus rau cov ntshav ntawm cov hlwb.Interestingly, adipotide muaj peev xwm pom cov hlab ntsha hauv cov rog rog los ntawm cov hlab ntsha thoob plaws hauv lub cev thiab yog li kev xaiv ntau heev.Kev tshawb fawb hauv cov liab qhia tau hais tias adipotide tsis yog tsuas yog ua rau poob phaus xwb, nws yeej txhawb cov tshuaj insulin rhiab heev thiab offsets qee qhov cuam tshuam ntawm hom 2 mob ntshav qab zib.

Khoom siv: Cov khoom no yog npaj los ua kev tshawb fawb tshuaj xwb.Qhov kev xaiv no tso cai rau kev siv cov tshuaj tshawb fawb nruj me ntsis rau hauv vitro kev sim thiab kev sim hauv kev sim nkaus xwb.Tag nrho cov ntaub ntawv khoom lag luam muaj nyob hauv lub vev xaib no yog rau kev kawm nkaus xwb.Kev taw qhia lub cev ntawm txhua yam rau tib neeg lossis tsiaj yog txwv tsis pub los ntawm txoj cai.Cov khoom no yuav tsum tsuas yog ua los ntawm cov ntawv tso cai, cov kws tshaj lij.Cov khoom no tsis yog tshuaj, khoom noj, lossis tshuaj pleev ib ce thiab yuav tsis raug misbranded, siv los yog mislabled raws li ib tug tshuaj, zaub mov los yog cosmetic.

Sequence: Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys—Gly-Gly–(Lys-Leu-Ala-Lys-Leu-Ala-Lys)2
Cov roj formula: C152H252N44O42
Molecular Luj: 2611.41 g / mol

Adipotide tau tsim thiab muab tso rau hauv theem I kev sim tshuaj hauv xyoo 2011 los tshawb xyuas nws lub peev xwm los tua cov rog rog.Kev ntsuam xyuas hauv rhesus liab qhia tias adipotide ua rau lub hom phiaj apoptosis hauv cov hlab ntsha ntawm cov nqaij dawb adipose (rog).Yog tsis muaj ntshav txaus, cov roj ntsha tsuas tuag.Cov txiaj ntsig tau tshwm sim yog kev poob phaus sai, txo qis hauv lub cev qhov hnyav (BMI), thiab txhim kho cov yam ntxwv ntawm insulin tsis kam.Interestingly, kev kho mob nrog adipotide thiab tom qab rog poob tsis tsuas yog txhim kho qhov hnyav, tab sis ua tau pab rau kev hloov hauv kev noj mov.Monkeys uas poob phaus nrog adipotide kuj pom tias txo qis hauv kev noj zaub mov [1].

A. Feem pua ​​​​qhov hnyav hauv pawg tswj hwm (xiav) piv rau cov uas tau kho nrog adipotide (ob koob tshuaj sib txawv, qhia hauv liab)
B. Feem pua ​​​​txo qis hauv BMI (tswj piv rau kev kho mob)

A. Qhia txog kev hloov pauv ntawm cov kev xav tau ntawm cov tshuaj insulin (chaw nyob hauv qab nkhaus) rau kev kho mob (liab) thiab tswj (xiav) pab pawg.AUC raug xam los ntawm kev xeem IVGTT.
B. Qhia cov insulinogenic Performance index rau ua ntej thiab tom qab kev kho mob (liab) thiab tswj (xiav) pab pawg.Cov pab pawg kho mob pom tias muaj kev txo qis hauv cov tshuaj insulin.
C. Hloov cov khoom noj biscuit hauv kev kho (liab) thiab tswj (xiav) pab pawg.

Lub hom phiaj ntawm adipotide rau cov hlab ntsha uas pab cov rog rog tuaj yeem kho los ntawm cov protein receptor hu ua txwv.Prohibitin yog ib daim nyias nyias uas tsuas pom muaj nyob rau hauv cov hlab ntsha uas pab cov rog dawb thiab hauv cov qog nqaij hlav cancer.Nws tau raug pom tias adipotide koom nrog cov protein no [2].Yog hais tias nws hloov tawm hais tias txwv tsis pub tsuas yog pom nyob rau hauv cov roj vasculature thiab qog nqaij hlav cancer, ces kev kuaj adipotide yuav yog lub luag hauj lwm rau kev txheeb xyuas lub hom phiaj ntawm cov rog uas tuaj yeem siv tsis yog rau kev kho mob nkaus xwb, tab sis rau kev kuaj mob thiab.