SR9009 ntsiav tshuaj 100 ntsiav tshuaj / lub raj mis

Khoom npe:SIB 9009

Spacification: 10 mg / ntsiav tshuaj 100 ntsiav tshuaj / lub raj mis

Nqe: $80 / lub raj mis

MOQ: 1 lub raj mis

Lab: LianFu Bio

Kev piav qhia

SR9009, REV-ERBagonist, nce kev tsim txom ntawm cov noob tswj los ntawm REV-ERBα / ERBβ (IC50: 670/800 nM).Los ntawm kev ua kom REV-ERB, SR9009 tuaj yeem txo cov kev ua haujlwm circadian locomotor thaum lub sijhawm tsaus ntuj thiab hloov cov qauv qhia ntawm cov core moos noob hauv hypothalami ntawm nas.Cov qauv circadian ntawm kev nthuav qhia ntawm cov kab mob metabolic hauv daim siab, cov leeg pob txha, thiab cov ntaub so ntswg adipose kuj tau hloov pauv hauv cov nas raug rau SR9009, ua rau muaj kev siv zog ntxiv.

SR9009 (100 mg / kg, ip, twv, rau 30 hnub) tuaj yeemtxo cov rog rogthiab markedlytxhim kho dyslipidemiathiabhyperglycemia.